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EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells

The highly conserved Rab guanosine triphosphatase (GTPase) Rab8 plays a role in exocytosis toward the polarized plasma membrane in eukaryotic cells. In murine Rab8-deficient small intestine cells, apical proteins are missorted into lysosomes. In this study, we identified a novel Rab8-interacting pro...

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Detalles Bibliográficos
Autores principales: Nakajo, Atsuhiro, Yoshimura, Shin-ichiro, Togawa, Hiroko, Kunii, Masataka, Iwano, Tomohiko, Izumi, Ayaka, Noguchi, Yuria, Watanabe, Ayako, Goto, Ayako, Sato, Toshiro, Harada, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739609/
https://www.ncbi.nlm.nih.gov/pubmed/26833786
http://dx.doi.org/10.1083/jcb.201508086