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The Role of Nitric Oxide and Reactive Oxygen Species in the Killing of Leishmania braziliensis by Monocytes from Patients with Cutaneous Leishmaniasis

Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis, presents an exaggerated Th1 response that is associated with ulcer development. Macrophages are the primary cells infected by Leishmania parasites and both reactive oxygen species (ROS) and nitric oxide (NO) are important in the c...

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Detalles Bibliográficos
Autores principales: Carneiro, Pedro Paulo, Conceição, Jacilara, Macedo, Michael, Magalhães, Viviane, Carvalho, Edgar M., Bacellar, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739692/
https://www.ncbi.nlm.nih.gov/pubmed/26840253
http://dx.doi.org/10.1371/journal.pone.0148084