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The Effect of Codon Mismatch on the Protein Translation System

Incorrect protein translation, caused by codon mismatch, is an important problem of living cells. In this work, a computational model was introduced to quantify the effects of codon mismatch and the model was used to study the protein translation of Saccharomyces cerevisiae. According to simulation...

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Detalles Bibliográficos
Autores principales: Zhang, Dinglin, Chen, Danfeng, Cao, Liaoran, Li, Guohui, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739699/
https://www.ncbi.nlm.nih.gov/pubmed/26840415
http://dx.doi.org/10.1371/journal.pone.0148302