The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium

Epithelial morphogenesis and stability are essential for normal development and organ homeostasis. The mouse neural plate is a cuboidal epithelium that remodels into a columnar pseudostratified epithelium over the course of 24 hr. Here we show that the transition to a columnar epithelium fails in mu...

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Detalles Bibliográficos
Autores principales: Grego-Bessa, Joaquim, Bloomekatz, Joshua, Castel, Pau, Omelchenko, Tatiana, Baselga, José, Anderson, Kathryn V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739759/
https://www.ncbi.nlm.nih.gov/pubmed/26809587
http://dx.doi.org/10.7554/eLife.12034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739759/
https://www.ncbi.nlm.nih.gov/pubmed/26809587
http://dx.doi.org/10.7554/eLife.12034

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