AMPylation matches BiP activity to client protein load in the endoplasmic reticulum

The endoplasmic reticulum (ER)-localized Hsp70 chaperone BiP affects protein folding homeostasis and the response to ER stress. Reversible inactivating covalent modification of BiP is believed to contribute to the balance between chaperones and unfolded ER proteins, but the nature of this modificati...

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Detalles Bibliográficos
Autores principales: Preissler, Steffen, Rato, Cláudia, Chen, Ruming, Antrobus, Robin, Ding, Shujing, Fearnley, Ian M, Ron, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739761/
https://www.ncbi.nlm.nih.gov/pubmed/26673894
http://dx.doi.org/10.7554/eLife.12621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739761/
https://www.ncbi.nlm.nih.gov/pubmed/26673894
http://dx.doi.org/10.7554/eLife.12621

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