DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

Identifying molecular alterations in normal tissue adjacent to cancer is important for understanding cancer aetiology and designing preventive measures. Here we analyse the DNA methylome of 569 breast tissue samples, including 50 from cancer-free women and 84 from matched normal cancer pairs. We use...

Descripción completa

Detalles Bibliográficos
Autores principales: Teschendorff, Andrew E, Gao, Yang, Jones, Allison, Ruebner, Matthias, Beckmann, Matthias W., Wachter, David L., Fasching, Peter A., Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740178/
https://www.ncbi.nlm.nih.gov/pubmed/26823093
http://dx.doi.org/10.1038/ncomms10478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740178/
https://www.ncbi.nlm.nih.gov/pubmed/26823093
http://dx.doi.org/10.1038/ncomms10478

Ejemplares similares