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E2F function in muscle growth is necessary and sufficient for viability in Drosophila

The E2F transcription factor is a key cell cycle regulator. However, the inactivation of the entire E2F family in Drosophila is permissive throughout most of animal development until pupation when lethality occurs. Here we show that E2F function in the adult skeletal muscle is essential for animal v...

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Detalles Bibliográficos
Autores principales: Zappia, Maria Paula, Frolov, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740182/
https://www.ncbi.nlm.nih.gov/pubmed/26823289
http://dx.doi.org/10.1038/ncomms10509