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Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis

Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular biochemical processes. The antibiotic concentrations ach...

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Detalles Bibliográficos
Autores principales: Shenje, Justin, Ifeoma Adimora-Nweke, F., Ross, Ian L., Ntsekhe, Mpiko, Wiesner, Lubbe, Deffur, Armin, McIlleron, Helen M., Pasipanodya, Jotam, Gumbo, Tawanda, Mayosi, Bongani M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740291/
https://www.ncbi.nlm.nih.gov/pubmed/26870790
http://dx.doi.org/10.1016/j.ebiom.2015.09.025