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Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis
Pericardial tuberculosis (TB) is associated with high therapy failure and high mortality rates. Antibiotics have to penetrate to site of infection at sufficient non-protein bound concentrations, and then enter bacteria to inhibit intracellular biochemical processes. The antibiotic concentrations ach...
Autores principales: | Shenje, Justin, Ifeoma Adimora-Nweke, F., Ross, Ian L., Ntsekhe, Mpiko, Wiesner, Lubbe, Deffur, Armin, McIlleron, Helen M., Pasipanodya, Jotam, Gumbo, Tawanda, Mayosi, Bongani M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740291/ https://www.ncbi.nlm.nih.gov/pubmed/26870790 http://dx.doi.org/10.1016/j.ebiom.2015.09.025 |
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