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Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes

The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes in relation to the ML ratio. Mycobacterial growth i...

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Detalles Bibliográficos
Autores principales: Naranbhai, Vivek, Fletcher, Helen A., Tanner, Rachel, O'Shea, Matthew K., McShane, Helen, Fairfax, Benjamin P., Knight, Julian C., Hill, Adrian V.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740301/
https://www.ncbi.nlm.nih.gov/pubmed/26870787
http://dx.doi.org/10.1016/j.ebiom.2015.09.027