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Cation Homeostasis in Red Cells From Patients With Sickle Cell Disease Heterologous for HbS and HbC (HbSC Genotype)

Sickle cell disease (SCD) in patients of HbSC genotype is considered similar, albeit milder, to that in homozygous HbSS individuals — but with little justification. In SCD, elevated red cell cation permeability is critical as increased solute loss causes dehydration and encourages sickling. Recently...

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Detalles Bibliográficos
Autores principales: Hannemann, A., Rees, D.C., Tewari, S., Gibson, J.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740305/
https://www.ncbi.nlm.nih.gov/pubmed/26870793
http://dx.doi.org/10.1016/j.ebiom.2015.09.026