Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis

Long-term linezolid use is limited by mitochondrial toxicity-associated adverse events (AEs). Within a prospective, randomized controlled trial of linezolid to treat chronic extensively drug-resistant tuberculosis, we serially monitored the translational competence of mitochondria isolated from peri...

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Detalles Bibliográficos
Autores principales: Song, Taeksun, Lee, Myungsun, Jeon, Han-Seung, Park, Yumi, Dodd, Lori E., Dartois, Véronique, Follman, Dean, Wang, Jing, Cai, Ying, Goldfeder, Lisa C., Olivier, Kenneth N., Xie, Yingda, Via, Laura E., Cho, Sang Nae, Barry, Clifton E., Chen, Ray Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740314/
https://www.ncbi.nlm.nih.gov/pubmed/26870788
http://dx.doi.org/10.1016/j.ebiom.2015.09.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740314/
https://www.ncbi.nlm.nih.gov/pubmed/26870788
http://dx.doi.org/10.1016/j.ebiom.2015.09.051

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