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The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most prevalent of the human prion diseases, which are fatal and transmissible neurodegenerative diseases caused by the infectious prion protein (PrP(Sc)). The origin of sCJD is unknown, although the initiating event is thought to be the stochastic mis...

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Detalles Bibliográficos
Autores principales: Moore, Roger A., Head, Mark W., Ironside, James W., Ritchie, Diane L., Zanusso, Gianluigi, Pyo Choi, Young, Priola, Suzette A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740439/
https://www.ncbi.nlm.nih.gov/pubmed/26840342
http://dx.doi.org/10.1371/journal.ppat.1005416