Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to exosomes were evaluated. CD4(+) Tconv, CD8(+) T or CD4(+) CD39(+) Treg were isolated from normal donors’ peripheral blood and co-incubated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Muller, Laurent, Mitsuhashi, Masato, Simms, Patricia, Gooding, William E., Whiteside, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740743/
https://www.ncbi.nlm.nih.gov/pubmed/26842680
http://dx.doi.org/10.1038/srep20254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740743/
https://www.ncbi.nlm.nih.gov/pubmed/26842680
http://dx.doi.org/10.1038/srep20254

Ejemplares similares