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Dual-functionalized liposomal delivery system for solid tumors based on RGD and a pH-responsive antimicrobial peptide

[D]-H(6)L(9), as a pH-responsive anti-microbial peptide (AMP), has been evidenced by us to be an excellent choice in tumor microenvironment-responsive delivery as it could render liposomes responsive to the acidified tumor microenvironment. However, [D]-H(6)L(9)-modified liposomes could not actively...

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Detalles Bibliográficos
Autores principales: Zhang, Qianyu, Lu, Libao, Zhang, Li, Shi, Kairong, Cun, Xingli, Yang, Yuting, Liu, Yayuan, Gao, Huile, He, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740748/
https://www.ncbi.nlm.nih.gov/pubmed/26842655
http://dx.doi.org/10.1038/srep19800