Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs

MeCP2 encodes a methyl-CpG-binding protein that plays a critical role in repressing gene expression, mutations of which lead to Rett syndrome and autism. PTEN is a critical tumor suppressor gene that is frequently mutated in human cancers and autism spectrum disorders. Various studies have shown tha...

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Detalles Bibliográficos
Autores principales: Lyu, Jing-Wen, Yuan, Bo, Cheng, Tian-Lin, Qiu, Zi-Long, Zhou, Wen-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740767/
https://www.ncbi.nlm.nih.gov/pubmed/26843422
http://dx.doi.org/10.1038/srep20392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740767/
https://www.ncbi.nlm.nih.gov/pubmed/26843422
http://dx.doi.org/10.1038/srep20392

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