A Dual Target-directed Agent against Interleukin-6 Receptor and Tumor Necrosis Factor α ameliorates experimental arthritis

A considerable proportion of patients with rheumatoid arthritis (RA) do not respond to monospecific agents. The purpose of our study was to generate a hybrid form of biologics, targeting tumor-necrosis factor alpha (TNFα) and interleukin-6 receptor (IL-6R), and determine its anti-arthritic propertie...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Youngkyun, Yi, Hyoju, Jung, Hyerin, Rim, Yeri Alice, Park, Narae, Kim, Juryun, Jung, Seung Min, Park, Sung-Hwan, Park, Young Woo, Ju, Ji Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740770/
https://www.ncbi.nlm.nih.gov/pubmed/26841833
http://dx.doi.org/10.1038/srep20150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740770/
https://www.ncbi.nlm.nih.gov/pubmed/26841833
http://dx.doi.org/10.1038/srep20150

Ejemplares similares