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A Dual Target-directed Agent against Interleukin-6 Receptor and Tumor Necrosis Factor α ameliorates experimental arthritis

A considerable proportion of patients with rheumatoid arthritis (RA) do not respond to monospecific agents. The purpose of our study was to generate a hybrid form of biologics, targeting tumor-necrosis factor alpha (TNFα) and interleukin-6 receptor (IL-6R), and determine its anti-arthritic propertie...

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Detalles Bibliográficos
Autores principales:	Kim, Youngkyun, Yi, Hyoju, Jung, Hyerin, Rim, Yeri Alice, Park, Narae, Kim, Juryun, Jung, Seung Min, Park, Sung-Hwan, Park, Young Woo, Ju, Ji Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740770/ https://www.ncbi.nlm.nih.gov/pubmed/26841833 http://dx.doi.org/10.1038/srep20150

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