Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression

We explore a model for ‘quenching-like' repression by studying synthetic bacterial enhancers, each characterized by a different binding site architecture. To do so, we take a three-pronged approach: first, we compute the probability that a protein-bound dsDNA molecule will loop. Second, we use...

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Detalles Bibliográficos
Autores principales: Brunwasser-Meirom, Michal, Pollak, Yaroslav, Goldberg, Sarah, Levy, Lior, Atar, Orna, Amit, Roee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740811/
https://www.ncbi.nlm.nih.gov/pubmed/26832446
http://dx.doi.org/10.1038/ncomms10407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740811/
https://www.ncbi.nlm.nih.gov/pubmed/26832446
http://dx.doi.org/10.1038/ncomms10407

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