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Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression
We explore a model for ‘quenching-like' repression by studying synthetic bacterial enhancers, each characterized by a different binding site architecture. To do so, we take a three-pronged approach: first, we compute the probability that a protein-bound dsDNA molecule will loop. Second, we use...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740811/ https://www.ncbi.nlm.nih.gov/pubmed/26832446 http://dx.doi.org/10.1038/ncomms10407 |