Affinity and competition for TBP are molecular determinants of gene expression noise

Cell-to-cell variation in gene expression levels (noise) generates phenotypic diversity and is an important phenomenon in evolution, development and disease. TATA-box binding protein (TBP) is an essential factor that is required at virtually every eukaryotic promoter to initiate transcription. While...

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Detalles Bibliográficos
Autores principales: Ravarani, Charles N. J., Chalancon, Guilhem, Breker, Michal, de Groot, Natalia Sanchez, Babu, M. Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740812/
https://www.ncbi.nlm.nih.gov/pubmed/26832815
http://dx.doi.org/10.1038/ncomms10417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740812/
https://www.ncbi.nlm.nih.gov/pubmed/26832815
http://dx.doi.org/10.1038/ncomms10417

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