ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

Endothelial-to-mesenchymal transition (EndMT) can cause loss of tight junctions, which in glomeruli are associated with albuminuria. Here we evaluated the role of EndMT in the development of albuminuria in diabetic nephropathy (DN). We demonstrated that EndMT occurs in the glomerular endothelium of...

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Detalles Bibliográficos
Autores principales: Peng, Hui, Li, Yuanqing, Wang, Cheng, Zhang, Jun, Chen, Yanru, Chen, Wenfang, Cao, Jin, Wang, Yanlin, Hu, Zhaoyong, Lou, Tanqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740844/
https://www.ncbi.nlm.nih.gov/pubmed/26842599
http://dx.doi.org/10.1038/srep20304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740844/
https://www.ncbi.nlm.nih.gov/pubmed/26842599
http://dx.doi.org/10.1038/srep20304

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