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ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy
Endothelial-to-mesenchymal transition (EndMT) can cause loss of tight junctions, which in glomeruli are associated with albuminuria. Here we evaluated the role of EndMT in the development of albuminuria in diabetic nephropathy (DN). We demonstrated that EndMT occurs in the glomerular endothelium of...
Autores principales: | Peng, Hui, Li, Yuanqing, Wang, Cheng, Zhang, Jun, Chen, Yanru, Chen, Wenfang, Cao, Jin, Wang, Yanlin, Hu, Zhaoyong, Lou, Tanqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740844/ https://www.ncbi.nlm.nih.gov/pubmed/26842599 http://dx.doi.org/10.1038/srep20304 |
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