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Role of transcription factor-mediated nucleosome disassembly in PHO5 gene expression

Studying nucleosome dynamics in promoter regions is crucial for understanding gene regulation. Nucleosomes regulate gene expression by sterically occluding transcription factors (TFs) and other non–histone proteins accessing genomic DNA. How the binding competition between nucleosomes and TFs leads...

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Detalles Bibliográficos
Autores principales: Kharerin, Hungyo, Bhat, Paike J., Marko, John F., Padinhateeri, Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740855/
https://www.ncbi.nlm.nih.gov/pubmed/26843321
http://dx.doi.org/10.1038/srep20319