Mito-priming as a method to engineer Bcl-2 addiction

Most apoptotic stimuli require mitochondrial outer membrane permeabilization (MOMP) in order to execute cell death. As such, MOMP is subject to tight control by Bcl-2 family proteins. We have developed a powerful new technique to investigate Bcl-2-mediated regulation of MOMP. This method, called mit...

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Detalles Bibliográficos
Autores principales: Lopez, Jonathan, Bessou, Margaux, Riley, Joel S., Giampazolias, Evangelos, Todt, Franziska, Rochegüe, Tony, Oberst, Andrew, Green, Douglas R., Edlich, Frank, Ichim, Gabriel, Tait, Stephen W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740867/
https://www.ncbi.nlm.nih.gov/pubmed/26833356
http://dx.doi.org/10.1038/ncomms10538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740867/
https://www.ncbi.nlm.nih.gov/pubmed/26833356
http://dx.doi.org/10.1038/ncomms10538

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