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Biosynthetic route towards saxitoxin and shunt pathway

Saxitoxin, the most potent voltage-gated sodium channel blocker, is one of the paralytic shellfish toxins (PSTs) produced by cyanobacteria and dinoflagellates. Recently, putative biosynthetic genes of PSTs were reported in these microorganisms. We previously synthesized genetically predicted biosynt...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740887/
https://www.ncbi.nlm.nih.gov/pubmed/26842222
http://dx.doi.org/10.1038/srep20340