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Early diagnosis of Alzheimer’s disease from elevated olfactory mucosal miR-206 level

MicroRNA-206, which suppresses the expression of brain-derived neurotrophic factor, is known to be elevated in the brains of Alzheimer’s disease (AD) patients. We performed intranasal biopsy of the olfactory epithelia of early dementia patients (n = 24) and cognitively healthy controls (n = 9). Pati...

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Detalles Bibliográficos
Autores principales: Moon, Jangsup, Lee, Soon-Tae, Kong, Il Gyu, Byun, Jung-Ick, Sunwoo, Jun-Sang, Shin, Jung-Won, Shim, Ji-Young, Park, Ji-Hyun, Jeon, Daejong, Jung, Keun-Hwa, Jung, Ki-Young, Kim, Dong-Young, Lee, Sang Kun, Kim, Manho, Chu, Kon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740889/
https://www.ncbi.nlm.nih.gov/pubmed/26842588
http://dx.doi.org/10.1038/srep20364