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Early diagnosis of Alzheimer’s disease from elevated olfactory mucosal miR-206 level
MicroRNA-206, which suppresses the expression of brain-derived neurotrophic factor, is known to be elevated in the brains of Alzheimer’s disease (AD) patients. We performed intranasal biopsy of the olfactory epithelia of early dementia patients (n = 24) and cognitively healthy controls (n = 9). Pati...
Autores principales: | Moon, Jangsup, Lee, Soon-Tae, Kong, Il Gyu, Byun, Jung-Ick, Sunwoo, Jun-Sang, Shin, Jung-Won, Shim, Ji-Young, Park, Ji-Hyun, Jeon, Daejong, Jung, Keun-Hwa, Jung, Ki-Young, Kim, Dong-Young, Lee, Sang Kun, Kim, Manho, Chu, Kon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740889/ https://www.ncbi.nlm.nih.gov/pubmed/26842588 http://dx.doi.org/10.1038/srep20364 |
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