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Zebrafish as a Model to Investigate Dynamin 2-Related Diseases

Mutations in the dynamin-2 gene (DNM2) cause autosomal dominant centronuclear myopathy (CNM) and dominant intermediate Charcot-Marie-Tooth (CMT) neuropathy type B (CMTDIB). As the relation between these DNM2-related diseases is poorly understood, we used zebrafish to investigate the effects of two d...

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Detalles Bibliográficos
Autores principales: Bragato, Cinzia, Gaudenzi, Germano, Blasevich, Flavia, Pavesi, Giulio, Maggi, Lorenzo, Giunta, Michele, Cotelli, Franco, Mora, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740890/
https://www.ncbi.nlm.nih.gov/pubmed/26842864
http://dx.doi.org/10.1038/srep20466