MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition

The activation/inactivation of HIF1α is precisely regulated in an oxygen-dependent manner. HIF1α is essential for hypoxia induced apoptosis and cell cycle arrest. Several recent studies indicated that the expression of miRNAs can be modulated by hypoxia. However, the involvement of miRNAs in the reg...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Xia, Wu-Yan, Liu, Shan-Shan, Chen, Hai-Yan, Sun, Lei, Liu, Meng-Yao, Li, Lin-Feng, Lu, Hong-Min, Fu, Yu-Jie, Wang, Pei, Wu, Hailong, Gao, Jian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740907/
https://www.ncbi.nlm.nih.gov/pubmed/26841847
http://dx.doi.org/10.1038/srep20489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740907/
https://www.ncbi.nlm.nih.gov/pubmed/26841847
http://dx.doi.org/10.1038/srep20489

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