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Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma

Transdifferentiation (TD) is a recent advancement in somatic cell reprogramming. The direct conversion of TD eliminates the pluripotent intermediate state to create cells that are ideal for personalized cell therapy. Here we provide evidence that TD-derived induced neural stem cells (iNSCs) are an e...

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Detalles Bibliográficos
Autores principales: Bagó, Juli R., Alfonso-Pecchio, Adolfo, Okolie, Onyi, Dumitru, Raluca, Rinkenbaugh, Amanda, Baldwin, Albert S., Miller, C. Ryan, Magness, Scott T., Hingtgen, Shawn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740908/
https://www.ncbi.nlm.nih.gov/pubmed/26830441
http://dx.doi.org/10.1038/ncomms10593