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Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma
Transdifferentiation (TD) is a recent advancement in somatic cell reprogramming. The direct conversion of TD eliminates the pluripotent intermediate state to create cells that are ideal for personalized cell therapy. Here we provide evidence that TD-derived induced neural stem cells (iNSCs) are an e...
Autores principales: | Bagó, Juli R., Alfonso-Pecchio, Adolfo, Okolie, Onyi, Dumitru, Raluca, Rinkenbaugh, Amanda, Baldwin, Albert S., Miller, C. Ryan, Magness, Scott T., Hingtgen, Shawn D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740908/ https://www.ncbi.nlm.nih.gov/pubmed/26830441 http://dx.doi.org/10.1038/ncomms10593 |
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