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Macromolecular crowding develops heterogeneous environments of gene expression in picoliter droplets

Understanding the dynamics of complex enzymatic reactions in highly crowded small volumes is crucial for the development of synthetic minimal cells. Compartmentalised biochemical reactions in cell-sized containers exhibit a degree of randomness due to the small number of molecules involved. However,...

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Detalles Bibliográficos
Autores principales: Hansen, Maike M. K., Meijer, Lenny H. H., Spruijt, Evan, Maas, Roel J. M., Roquelles, Marta Ventosa, Groen, Joost, Heus, Hans A., Huck, Wilhelm T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740931/
https://www.ncbi.nlm.nih.gov/pubmed/26501750
http://dx.doi.org/10.1038/nnano.2015.243