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The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3

BACKGROUND: Regulation of gene expression by histone-modifying enzymes is essential to control cell fate decisions and developmental processes. Two histone-modifying enzymes, RPD3, a deacetylase, and dKDM5/LID, a demethylase, are present in a single complex, coordinated through the SIN3 scaffold pro...

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Detalles Bibliográficos
Autores principales: Gajan, Ambikai, Barnes, Valerie L., Liu, Mengying, Saha, Nirmalya, Pile, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740996/
https://www.ncbi.nlm.nih.gov/pubmed/26848313
http://dx.doi.org/10.1186/s13072-016-0053-9