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CD146(+) mesenchymal stem cells display greater therapeutic potential than CD146(–) cells for treating collagen-induced arthritis in mice

BACKGROUND: The characteristics and therapeutic potential of subtypes of mesenchymal stem cells (MSCs) are largely unknown. In this study, CD146(+) and CD146(–) MSCs were separated from human umbilical cords, and their effects on regulatory T cells (Tregs), Th17 cells, chondrogenesis, and osteogenes...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Chi, Liu, Fei-Lan, Sytwu, Huey-Kang, Tsai, Chang-Youh, Chang, Deh-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741021/
https://www.ncbi.nlm.nih.gov/pubmed/26841872
http://dx.doi.org/10.1186/s13287-016-0285-4