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Estimating and comparing microbial diversity in the presence of sequencing errors

Estimating and comparing microbial diversity are statistically challenging due to limited sampling and possible sequencing errors for low-frequency counts, producing spurious singletons. The inflated singleton count seriously affects statistical analysis and inferences about microbial diversity. Pre...

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Detalles Bibliográficos
Autores principales: Chiu, Chun-Huo, Chao, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741086/
https://www.ncbi.nlm.nih.gov/pubmed/26855872
http://dx.doi.org/10.7717/peerj.1634