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Estimating and comparing microbial diversity in the presence of sequencing errors
Estimating and comparing microbial diversity are statistically challenging due to limited sampling and possible sequencing errors for low-frequency counts, producing spurious singletons. The inflated singleton count seriously affects statistical analysis and inferences about microbial diversity. Pre...
Autores principales: | Chiu, Chun-Huo, Chao, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741086/ https://www.ncbi.nlm.nih.gov/pubmed/26855872 http://dx.doi.org/10.7717/peerj.1634 |
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