miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability

The evolutionarily conserved miR-302 family of microRNAs is expressed during early mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice results in a fully penetrant late embryonic lethal phenotype. Knockout embryos have an anterior neural tube closure defect associate...

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Detalles Bibliográficos
Autores principales: Parchem, Ronald J., Moore, Nicole, Fish, Jennifer L., Parchem, Jacqueline G., Braga, Tarcio T., Shenoy, Archana, Oldham, Michael C., Rubenstein, John L.R., Schneider, Richard A., Blelloch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741278/
https://www.ncbi.nlm.nih.gov/pubmed/26212322
http://dx.doi.org/10.1016/j.celrep.2015.06.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741278/
https://www.ncbi.nlm.nih.gov/pubmed/26212322
http://dx.doi.org/10.1016/j.celrep.2015.06.074

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