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Agile CD22 nanoclusters run rings around fenced BCR

B lymphocytes are key players in host defence, but also autoimmune diseases. Their survival depends upon tonic signals transduced by surface immunoglobulin (BCR) and the process leading to antibody secretion is initiated by interaction of BCR with a cognate antigen. CD22 limits signalling of the BCR...

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Detalles Bibliográficos
Autores principales: Depoil, David, Dustin, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741298/
https://www.ncbi.nlm.nih.gov/pubmed/26746852
http://dx.doi.org/10.15252/embj.201593745