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TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic

Macroautophagy requires membrane trafficking and remodelling to form the autophagosome and deliver its contents to lysosomes for degradation. We have previously identified the TBC domain‐containing protein, TBC1D14, as a negative regulator of autophagy that controls delivery of membranes from RAB11‐...

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Detalles Bibliográficos
Autores principales: Lamb, Christopher A, Nühlen, Stefanie, Judith, Delphine, Frith, David, Snijders, Ambrosius P, Behrends, Christian, Tooze, Sharon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741301/
https://www.ncbi.nlm.nih.gov/pubmed/26711178
http://dx.doi.org/10.15252/embj.201592695