Effects of a novel Nodal-targeting monoclonal antibody in melanoma

Nodal is highly expressed in various human malignancies, thus supporting the rationale for exploring Nodal as a therapeutic target. Here, we describe the effects of a novel monoclonal antibody (mAb), 3D1, raised against human Nodal. In vitro treatment of C8161 human melanoma cells with 3D1 mAb shows...

Descripción completa

Detalles Bibliográficos
Autores principales: Strizzi, Luigi, Sandomenico, Annamaria, Margaryan, Naira V., Focà, Annalia, Sanguigno, Luca, Bodenstine, Thomas M., Chandler, Grace S., Reed, David W., Gilgur, Alina, Seftor, Elisabeth A., Seftor, Richard E.B., Khalkhali-Ellis, Zhila, Leonardi, Antonio, Ruvo, Menotti, Hendrix, Mary J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741437/
https://www.ncbi.nlm.nih.gov/pubmed/26460952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741437/
https://www.ncbi.nlm.nih.gov/pubmed/26460952

Ejemplares similares