Arenobufagin intercalates with DNA leading to G(2) cell cycle arrest via ATM/ATR pathway

Arenobufagin, a representative bufadienolide, is the major active component in the traditional Chinese medicine Chan'su. It possesses significant antineoplastic activity in vitro. Although bufadienolide has been found to disrupt the cell cycle, the underlying mechanisms of this disruption are n...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Li-Juan, Peng, Qun-Long, Wang, Long-Hai, Xu, Jun, Liu, Jun-Shan, Li, Ying-Jie, Zhuo, Zhen-Jian, Bai, Liang-Liang, Hu, Li-Ping, Chen, Wei-Min, Ye, Wen-Cai, Zhang, Dong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741450/
https://www.ncbi.nlm.nih.gov/pubmed/26485758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741450/
https://www.ncbi.nlm.nih.gov/pubmed/26485758

Ejemplares similares