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The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer

Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal metastatic castration-resistant disease. Here we used RNA-Seq coupled with bioinfor...

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Detalles Bibliográficos
Autores principales: Munkley, Jennifer, Oltean, Sebastian, Vodák, Daniel, Wilson, Brian T., Livermore, Karen E., Zhou, Yan, Star, Eleanor, Floros, Vasileios I., Johannessen, Bjarne, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Skotheim, Rolf I., Robson, Craig N., Leung, Hing Y., Harries, Lorna W., Rajan, Prabhakar, Mills, Ian G., Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741458/
https://www.ncbi.nlm.nih.gov/pubmed/26452038