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The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal metastatic castration-resistant disease. Here we used RNA-Seq coupled with bioinfor...
Autores principales: | Munkley, Jennifer, Oltean, Sebastian, Vodák, Daniel, Wilson, Brian T., Livermore, Karen E., Zhou, Yan, Star, Eleanor, Floros, Vasileios I., Johannessen, Bjarne, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Skotheim, Rolf I., Robson, Craig N., Leung, Hing Y., Harries, Lorna W., Rajan, Prabhakar, Mills, Ian G., Elliott, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741458/ https://www.ncbi.nlm.nih.gov/pubmed/26452038 |
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