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The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway

Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. Here we show that TGR5 is a suppressor of gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway. We firstly show that TGR...

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Detalles Bibliográficos
Autores principales: Guo, Cong, Su, Jia, Li, Zhijun, Xiao, Rui, Wen, Jianxun, Li, Yanyan, Zhang, Meng, Zhang, Xueting, Yu, Donna, Huang, Wendong, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741461/
https://www.ncbi.nlm.nih.gov/pubmed/26417930