Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors

Highly malignant tumors express high levels of the minichromosome maintenance 2 (MCM2) protein, which is associated with advanced tumor grade, advanced stage, and poor prognosis. In a previous study, we showed that Friend leukemia virus (FLV) envelope protein gp70 bound MCM2, impaired its nuclear tr...

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Detalles Bibliográficos
Autores principales: Abe, Shinya, Yamamoto, Kouhei, Kurata, Morito, Abe-Suzuki, Shiho, Horii, Rie, Akiyama, Futoshi, Kitagawa, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741497/
https://www.ncbi.nlm.nih.gov/pubmed/26430873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741497/
https://www.ncbi.nlm.nih.gov/pubmed/26430873

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