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Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration

The liver and pancreas originate from overlapping embryonic regions, and single-cell lineage tracing in zebrafish has shown that Bone morphogenetic protein 2b (Bmp2b) signaling is essential for determining the fate of bipotential hepatopancreatic progenitors towards the liver or pancreas. Despite it...

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Detalles Bibliográficos
Autores principales: Xu, Jin, Cui, Jiaxi, Del Campo, Aranzazu, Shin, Chong Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741517/
https://www.ncbi.nlm.nih.gov/pubmed/26845333
http://dx.doi.org/10.1371/journal.pgen.1005831