Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

Here, we developed an isogenic cell model of “stemness” to facilitate protein biomarker discovery in breast cancer. For this purpose, we used knowledge gained previously from the study of the mouse mammary tumor virus (MMTV). MMTV initiates mammary tumorigenesis in mice by promoter insertion adjacen...

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Detalles Bibliográficos
Autores principales: Lamb, Rebecca, Bonuccelli, Gloria, Ozsvári, Béla, Peiris-Pagès, Maria, Fiorillo, Marco, Smith, Duncan L., Bevilacqua, Generoso, Mazzanti, Chiara Maria, McDonnell, Liam A., Naccarato, Antonio Giuseppe, Chiu, Maybo, Wynne, Luke, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741544/
https://www.ncbi.nlm.nih.gov/pubmed/26421711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741544/
https://www.ncbi.nlm.nih.gov/pubmed/26421711

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