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Endothelial tyrosine kinase receptor B prevents VE-cadherin cleavage and protects against atherosclerotic lesion development in ApoE−/− mice

Tyrosine kinase receptor B (TrkB) is a high-affinity receptor for brain-derived neurotrophic factor (BDNF). In addition to its nervous system functions, TrkB is also expressed in the aortic endothelium. However, the effects of endothelial TrkB signaling on atherosclerosis remained unknown. Immunoflu...

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Detalles Bibliográficos
Autores principales: Jiang, Hong, Huang, Shuhong, Li, Xinyun, Li, Xian, Huang, Shanying, Zhang, Yun, Chen, Zhe-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741558/
https://www.ncbi.nlm.nih.gov/pubmed/26431274