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A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins

We have created a novel fluorescent model of a human ovarian carcinoma xenograft overexpressing receptor HER2, a promising molecular target of solid tumors. The model is based on a newly generated SKOV-kat cell line stably expressing far-red fluorescent protein Katushka. Katushka is most suitable fo...

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Detalles Bibliográficos
Autores principales: Zdobnova, Tatiana, Sokolova, Evgeniya, Stremovskiy, Oleg, Karpenko, Dmitry, Telford, William, Turchin, Ilya, Balalaeva, Irina, Deyev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741577/
https://www.ncbi.nlm.nih.gov/pubmed/26436696